info.mycology@witshealth.co.za

Our SHARE-CM
Project

Single, High-dose AmBisome to Reduce Excess mortality from Cryptococcal Meningitis

Our SHARE-CM
Project

Single, High-dose AmBisome to Reduce Excess mortality from Cryptococcal Meningitis

Project Overview

Project title: Single, High-dose AmBisome to Reduce Excess mortality from Cryptococcal Meningitis

Abbreviation: SHARE-CM

Start date: 01/09/2021
End date: 30/09/2026

The purpose of this project is to leverage individual and institutional experience in delivering the ACTA and AMBITION-cm short-course regimens for HIV-associated cryptococcal meningitis to facilitate widespread implementation across Botswana, Malawi, Uganda and Zimbabwe with the ultimate aim of reducing mortality from cryptococcal meningitis in real-world settings. SHARE-CM is co-funded by the Centers for Disease Control and Prevention (CDC).

Key Objectives

  • Improved in-country and international partnerships to support execution of HIV-associated fungal disease public health work.
  • Increased public awareness and knowledge of fungal diseases.
  • Increased provider awareness, knowledge and support for identifying and diagnosing fungal infections.
  • Improved treatment of HIV-associated fungal infections.

Team Members

  • Dr David Lawrence
  • Prof Tom Harrison (CSGUL)
  • Dr Eltas Dziwani (MLWT)
  • Professor David Meya (IDI)
  • Professor Joe Jarvis
  • Dr Tshepo Leeme (BHP)
  • Professor Henry Mwandumba(MLWT)
  • Dr Constantine Mutaba (UoZ)
  • Professor Nelesh Govender (WITS)
  • Professor Mosepele (BHP)
  • Dr Jane Gakuru (IDI)
  • Professor Chiratidzo Ndhlovu (UoZ)

Project Partners

Project Funders